Chlorisondamine diiodide

产品名称：

96750-66-2
Chlorisondamine diiodide
4,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-2H-isoindolium diiodide

产品介绍：

产品说明

应用

Chlorisondamine diiodide has been used:

as a nicotinic receptor antagonist to test its effect on trinitrobenzene sulfonic acid (TNBS)-induced colitis
as an irreversible nicotinic acetylcholine(nAChR) blocker to pre-treat brain samples to test its effect on cytochrome P450 2B (CYP2B) induction
as a ganglionic blocker to test its effect on regulating corticosterone levels in rat with chronic stress

包装

10, 50 mg in glass bottle

生化/生理作用

Chlorisondamine diiodide mediates ganglionic and central blockade.
Irreversible, long-lasting nicotinic acetylcholine receptor antagonist.

特点和优势

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₄H₂₀Cl₄I₂N₂
分子量	611.94
MDL编号	MFCD01074794
PubChem化学物质编号	24724443
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	solid
储存条件	protect from light
颜色	white
溶解性	H₂O: ≥2 mg/mL DMSO: >20 mg/mL
储存温度	2-8℃
SMILES string	[I-].[I-].C[N+](C)(C)CC[N+]1(C)Cc2c(Cl)c(Cl)c(Cl)c(Cl)c2C1
InChI	1S/C14H20Cl4N2.2HI/c1-19(2,3)5-6-20(4)7-9-10(8-20)12(16)14(18)13(17)11(9)15;;/h5-8H2,1-4H3;2*1H/q+2;;/p-2
InChI key	FPNVAOZHQUJJJQ-UHFFFAOYSA-L

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H400
预防措施声明	P273 - P301 + P312 + P330
危险分类	Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves