产品说明
应用
Cholesterol 5β,6β-epoxide was used to treat PC12 cells or HepG2 and Caco-2 cells to study the effects of cholesterol oxidation.
包装
10 mg in glass bottle
50 mg in poly bottle
生化/生理作用
Cholesterol 5β,6β-epoxide is an oxysterol produced as an oxidation product of cholesterol. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation.
基本信息
经验(实验)分子式 | C27H46O2 |
分子量 | 402.65 |
MDL编号 | MFCD00201258 |
PubChem化学物质编号 | 24892511 |
产品性质
质量水平 | 100 |
测定 | ≥98% |
形式 | powder |
官能团 | epoxy |
运输 | ambient |
储存温度 | room temp |
SMILES string | [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@]3(O4)[C@H]4C2)([H])CC[C@@]5(C)[C@@]1([H])CC[C@]5([H])[C@]([H])(C)CCCC(C)C |
InChI | 1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28H,6-16H2,1-5H3 |
InChI key | PRYIJAGAEJZDBO-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
Sigma-Aldrich