Anti-CLAN Protein (CARD12) antibody produced in rabbit

产品说明

一般描述

NLR family CARD domain-containing protein 4 is a protein encoded by NLRC4 gene in humans. NLRC4 is also known as CLAN, IPAF, CLAN1, CLANA, CLANB, CLANC, CLAND, CARD12 and CLR2. It is a member of the Ced4/ Apaf-1 family.

免疫原

peptide corresponding to the N-terminus of the human CLAN protein, both A and B isoforms.

应用

Anti-CLAN Protein (CARD12) antibody produced in rabbit is suitable for western blotting at a dilution of 1:500-1:1,000 using human lung lysates.

生化/生理作用

CLAN (CARD12) induces apoptosis and plays a critical role in NF-κB signaling pathways. CARD12 plays an important role during activation of caspase-1 and is dependent on the nucleotide-binding site. It prevents motor-neuron apoptosis induced by a variety of signals.

外形

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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