Carboxy-PTIO, Sodium Salt-Calbiochem

产品说明

一般描述

Reacts with nitric oxide at pH 7.4, resulting in the generation of NO₂^-/NO₃^- with a rate constant of 1 x 10⁴ M^-1sec^-1. Prevents SIN-1 induced endothelial cell death. Reported to have potent therapeutic value in endotoxin shock through its nitric oxide scavenging action.
Reacts with nitric oxide at pH 7.4, resulting in the generation of NO₂^-/NO₃^- with a rate constant of 1 x 10⁴ M^-1sec^-1. Prevents SIN-1 induced endothelial cell death. Has potent therapeutic value in endotoxin shock through its nitric oxide scavenging action.

包装

10 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Nitric oxide scavenging action

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, refrigerate (4°C). Aqueous stock solutions are stable for up to 1 week at 4°C.

其他说明

Ishii, M., et al., 1999. J. Cardiovasc. Pharmacol. 33, 295.
Amano, F., and Nova, J. 1995. FEBS Lett.368, 425.
Hogg, N., et al. 1995. Free Radical Res.22, 47.
Az-ma, T., et al. 1994. Life Sci.54, 185.
Yoshida, M., et al. 1994. Biochem. Biophys. Res. Commun.202, 923.
Akaike, T., et al. 1993. Biochemistry32, 827.
Yoshida, K., et al. 1993. Infect. Immun.61, 3552.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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