产品说明
一般描述
Diosmetin is a methylated aglycone flavone of diosmin. It is present abundantly in citrus fruits, Olea europaea L. (olive tree) leaves, and in the legume of Acacia farnesiana tree.
应用
Diosmetin has been used to test its protective effects on chronic stress memory and cognitive impairment in mice model.
包装
100, 500 mg in poly bottle
10 mg in glass insert
生化/生理作用
Diosmetin exhibits anti-inflammatory, anti-cancer, antimicrobial, phytoestrogenic, and neuroprotective properties. It displays cytoprotective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by inhibiting nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome and activating nuclear factor erythroid 2–related factor 2 (Nrf2).
Flavonoid from Citrus limon. Antioxidant. Inhibits carcinogen activation by inhibiting the CYP1A1 enzyme.
基本信息
| 经验(实验)分子式 | C16H12O6 |
| 分子量 | 300.26 |
| Beilstein | 294492 |
| EC 号 | 208-291-8 |
| MDL编号 | MFCD00017425 |
| PubChem化学物质编号 | 329798848 |
| NACRES | NA.25 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% (HPLC) |
| 颜色 | light yellow to yellow |
| 溶解性 | DMSO: 1 mg/mL, clear, faintly yellow to greenish-yellow |
| 储存温度 | 2-8℃ |
| SMILES string | COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O)cc3O2 |
| InChI | 1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3 |
| InChI key | MBNGWHIJMBWFHU-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
