2′,3′-Didehydro-3′-deoxythymidine

产品名称：

3056-17-5
2′,3′-Didehydro-3′-deoxythymidine
Stavudine
1-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-(1H,3H)-dione
d4T
1-(2,3-Dideoxy-β-D-glycero-pent-2-enofuranosyl)thymine
2′,3′-Anhydrothymidine
2′,3′-二脱氢-3′-脱氧胸苷

产品介绍：

产品说明

一般描述

2′,3′-Didehydro-3′-deoxythymidine (d4T), a pyrimidine analogue is the inhibitor of reverse transcriptase.

应用

2′,3′-Didehydro-3′-deoxythymidine has been used in cell treatment. It has also been used as a drug in Caenorhabditis elegans to study drug induced mitochondrial toxicity. It has also been used in the preclinical evaluation of GS-9160.

包装

10, 50 mg in poly bottle

生化/生理作用

2′,3′-Didehydro-3′-deoxythymidine is a nucleoside analog, which inhibits HIV replication in vitro. Stavudine has the ability to enter the cells by non-facilitated diffusion. It possesses inhibitory activity against moloney murine leukemia virus, friend murine leukemia virus and simian immunodeficiency virus.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D1413.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式	C₁₀H₁₂N₂O₄
分子量	224.21
MDL编号	MFCD00132921
PubChem化学物质编号	24278356
NACRES	NA.77

产品性质

质量水平	200
测定	≥98% (TLC)
储存温度	−20℃
SMILES string	CC1=CN([C@@H]2O[C@H](CO)C=C2)C(=O)NC1=O
InChI	1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1
InChI key	XNKLLVCARDGLGL-JGVFFNPUSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)