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Milli-Mark® Anti-FcεRI Antibody, γ subunit-FITC

Milli-Mark® Anti-FcεRI Antibody, γ subunit-FITC

品牌
Sigma-Aldrich
货号
FCABS400F
规格纯度
Milli-Mark®, from rabbit
参考价格
4681.07 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Milli-Mark® Anti-FcεRI Antibody, γ subunit-FITC
Fc fragment of IgE high affinity I receptor for gamma polypeptide, Fc-epsilon RI-gamma, FceRI gamma, IgE Fc receptor subunit gamma, Immunoglobulin E receptor, high affinity,gamma chain
Milli-Mark 抗-FcεRI 抗体,γFITC 亚基
产品介绍:

产品说明

一般描述

Type I allergic reactions are mediated through the IgE high affinity receptor (FceRI). When a multivalent antigen is presented, a redistribution of the monomeric IgE FceRI receptor complexes cause the degranulation of mast cells and basophils, resulting in the subsequent release of factors responsible for type I allergic reactions. The FceRI receptor is a tetrameric complex, consisting of an a-chain, b-chain and a dimeric g-chain. While the a-chain is primarily involved with the binding of IgE, the signal is transferred through the g subunit, which contains the immunoreceptor tyrosine activation motifs (ITAM) critical for initiating receptor mediated signal transduction through the Syk and Lyn tyrosine kinases. The FceRI receptor is able to engage and disengage the IgE, providing a versatile model for studying the function of kinase coupled receptors.

特异性

Recognizes and is specific for FcεRI, γ-subunit.

免疫原

Synthetic peptide corresponding to amino acids 80-86 of γ-subunit of Fc receptors.

应用

Research Sub Category
Inflammation & Autoimmune Mechanisms
Milli-Mark Anti-FcεRI Antibody, γ subunit-FITC is an antibody against FcεRI for use in FC.
Research Category
Inflammation & Immunology

质量

Evaluated by flow cytometry using RBL cells.

目标描述

10 kDa Calculated

外形

Purified rabbit polyclonal IgG conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Protein A purified

储存及稳定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析说明

Control
RBL cells

其他说明

Unconjugated antibody (Cat No. 06-727) has been shown to work on Human and Mouse.

法律信息

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物FITC conjugate
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆polyclonal
species reactivityhuman, rat, mouse
manufacturer/tradenameMilli-Mark®
technique(s)flow cytometry: suitable
同位素/亚型IgG
NCBI登记号NP_004097
UniProt登记号P30273
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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