Anti-Glycine Receptor α3 antibody produced in rabbit

产品说明

一般描述

Glycine receptors are group I ligand-gated ion channel (LGICs) proteins that belong to the Cys loop receptor family. It has been reported that there are three polypeptide species: GlyR (48kDa) and GlyR (58kDa) subunits and a tightly bound cytosolic scaffolding protein (93kDa) later named gephyrin. It appears to exist as a heteropentameric proteins with an oligomeric transmembrane protein made up of three α and two β subunits. It has been identified that glycine receptors contains four subunit isoforms (α1-α4) and a single β subunit forming GlyR. It helps in mediating synaptic inhibition in the spinal cord, retina and brain of vertebrates.

特异性

Rat, mouse, and human sequences are identical.

免疫原

synthetic peptide corresponding to residues 355-368 of rat glycine receptor α3.

应用

Anti-Glycine Receptor α3 antibody is suitable for western blot at a dilution of 1:200 using rat brain membranes.

目标描述

Glycine Receptor α3 encodes the α3 subunit of the neuronal glycine receptor, a ligand-gated chloride channel composed of ligand-binding α and structural β polypeptides.

外形

Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA, and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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