产品说明
包装
50, 250 mg in glass bottle
生化/生理作用
Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.
特点和优势
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
法律信息
Sold for research purposes under agreement from GlaxoSmithKline
基本信息
| 经验(实验)分子式 | C23H21N7 |
| 分子量 | 395.46 |
| MDL编号 | MFCD04974495 |
| PubChem化学物质编号 | 24278451 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 颜色 | yellow |
| 溶解性 | DMSO: ≥20 mg/mL |
| 创始人 | GlaxoSmithKline |
| SMILES string | CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1 |
| InChI | 1S/C23H21N7/c1-29(2)22-11-19-20(13-24-22)25-15-26-23(19)28-18-8-9-21-17(10-18)12-27-30(21)14-16-6-4-3-5-7-16/h3-13,15H,14H2,1-2H3,(H,25,26,28) |
| InChI key | DYYZXRCFCVDSKD-UHFFFAOYSA-N |
| Gene Information | human ... EGFR(1956), ERBB2(2064) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
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