产品说明

一般描述

Pancreatic α-amylase is produced by the pancreatic acinar cells and released into the duodenum. It is a major molecule of pancreatic fluid.

应用

α-Amylase from hog pancreas has been used:

• in the in vitro digestion system to study the hydrolysis of pea globulins
• in vitro α-amylase inhibition study
• to prepare digestive juice (salivary juice) for the in vitro model of the human digestion system

生化/生理作用

α-Amylase is a starch hydrolase, for glucose production, important for energy acquisition. It catalyzes the hydrolysis of α-1,4-glycosidic linkages in starch to form glucose, maltose, and maltotriose units. In mammals, α-amylase regulates the sugar assimilation by reducing the glucose uptake by Na⁺/glucose cotransporter 1 (SGLT1) and stimulating glycoprotein N-glycans mediated starch digestion. α-Amylase inhibitors are associated with the treatment of type 2 diabetes mellitus. α-Amylases are widely known industrial enzymes used in food, detergent, textile, fermentation, and pharmaceutical industries.

单位定义

1单位酶相当于在pH 6.9和25℃条件下，每分钟释放1 μmol麦芽糖所需的酶量(淀粉符合Zulkowsky，货号85642，作为底物)

其他说明

最佳酸碱度和温度分别为6.9和53℃；钙是活性所必需的，也能防止胰蛋白酶降解；表征。

基本信息

产品性质

安全信息

象形图
警示用语：	Danger
危险声明	H334
预防措施声明	P261 - P342 + P311
危险分类	Resp. Sens. 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Faceshields, Gloves