产品说明
一般描述
Cell permeable. Inhibits the induction of nitric oxide synthase activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells. Inhibits NF-κB activation and HIV replication in lymphocytes.
包装
100 mg in Plastic ampoule
生化/生理作用
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Induction of nitric oxide synthase activity in rat alveolar macrophages
警告
Toxicity: Irritant (B)
重悬
Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 3 months at -20°C.
From Catalog:
Desc. Field- added "cell-permeable"
其他说明
Tsai, J.C., et al. 1996. J. Biol. Chem.271, 3667.
Pan, Z., et al. 1995. J. Biol. Chem.270, 7787.
Bessho, R., et al. 1994. Biochem. Pharmacol.48, 1883.
Sherman, M.P., et al. 1993. Biochem. Biophys. Res. Commun.191, 1301.
Schreck, R., et al. 1992. J. Exp. Med.175, 1181.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C5H12N2S2 |
分子量 | 164.29 |
MDL编号 | MFCD00012720 |
产品性质
质量水平 | 100 |
测定 | ≥98% (titration) |
形式 | solid |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze desiccated (hygroscopic) |
颜色 | white |
溶解性 | water: 1 mg/mL |
运输 | ambient |
储存温度 | 2-8℃ |
InChI | 1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3 |
InChI key | MDDIUTVUBYEEEM-UHFFFAOYSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich