产品说明
一般描述
A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
A stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
包装
500 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Free radical scavenger and nitric oxide spin trap
警告
Toxicity: Harmful (C)
重悬
Prepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).
其他说明
Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med.29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo)41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C9H18NO2 |
| 分子量 | 172.24 |
| MDL编号 | MFCD00006478 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% total nitrogen (N) basis |
| 形式 | crystals powder |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze protect from light |
| 颜色 | orange |
| 溶解性 | DMSO: 5 mg/mL ethanol: soluble water: soluble |
| 运输 | ambient |
| 储存温度 | −20℃ |
| InChI | 1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3 |
| InChI key | UZFMOKQJFYMBGY-UHFFFAOYSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H302 - H318 |
| 预防措施声明 | P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501 |
| 危险分类 | Acute Tox. 4 Oral - Eye Dam. 1 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | 294.8 °F - DIN 51758 |
| 闪点(C) | 146 ℃ - DIN 51758 |
Sigma-Aldrich
m.cnreagent.com
