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Anti-Calcineurin A/PP2B catalytic unit Antibody

品牌
Sigma-Aldrich
货号
07-068-I
规格纯度
from rabbit, purified by affinity chromatography
参考价格
5016.79 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Calcineurin A/PP2B catalytic unit Antibody
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit beta isoform
产品介绍:

产品说明

一般描述

Calcineurin/PP2B Aβ, also known as Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform, and encoded by the gene PPP3CB/CALNA2/CALNB/CNA2, is a calcium dependent, calmodulin stimulated catalytic subunit protein phosphatase critical in the function of Calcineurin an important phosphatase governing immune responses such as T cell activation and the T cell immune response. Calcineurin is a heterodimeric protein consisting of a catalytic subunit Calcineurin A, which contains an active site dinuclear metal center, and a tightly associated, myristoylated, Ca(2+)-binding subunit, Calcineurin B. Calcineurin/PP2B Aβ is the beta isoform of the catalytic active site of the subunit A of Calcineurin. Calcineurin also plays pivotal roles in signaling transduction cascades in a variety of other immune cells as well as non-immune cells like myocytes and neurons.

免疫原

KLH-conjugated linear peptide corresponding to rat Calcineurin A/PP2B catalytic unit near the C-terminus.
Epitope: Near C-terminus

应用

Research Sub Category
Metabolic Hormones & Receptors
Research Category
Signaling
Immunoprecipitation Analysis: 5 µg from a representative lot immunoprecipitated Calcineurin A/PP2B catalytic unit in 500 µg of mouse brain tissue lysate.
This Anti-Calcineurin A/PP2B catalytic unit antibody is validated for use in western blotting & IP for the detection of Calcineurin A/PP2B catalytic unit.

质量

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Calcineurin A/PP2B catalytic unit in 10 µg of human brain tissue lysate.

目标描述

~57 kDa observed

联系

Replaces: 07-068

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivityrat, human, mouse
technique(s)immunoprecipitation (IP): suitable
western blot: suitable
NCBI登记号NP_058738
UniProt登记号P20651
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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