产品说明
一般描述
Matrix metalloproteinase-24 (MMP-24) is expressed majorly in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20.
特异性
Reacts with reduced and native MMP-24. Recognizes only the pro-form of MMP-24 and not the active forms.
免疫原
synthetic peptide corresponding to the propeptide region of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5).
生化/生理作用
Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.
外形
Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide
基本信息
MDL编号 | MFCD03097033 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous glycerol solution |
分子量 | antigen 65 kDa |
species reactivity | mouse, human |
浓度 | ~1 mg/mL |
technique(s) | flow cytometry: suitable immunohistochemistry (frozen sections): suitable immunoprecipitation (IP): suitable indirect ELISA: suitable western blot: 1:2,000 |
UniProt登记号 | Q9Y5R2 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... MMP24(10893) mouse ... Mmp24(17391) |
Sigma-Aldrich