NBI 27914

产品名称：

184241-44-9
NBI 27914
5-Chloro-4-(N-(cyclopropyl)methyl-N-propylamino)-2-methyl-6-(2,4,6-trichlorophenyl)aminopyridine

产品介绍：

产品说明

应用

NBI 27914 has been used as acorticotropin-releasing hormone receptor (CRHR1) antagonist:

to study its effects on steroidogenic gene expression in GD15 mouse testis
to study its effects on amyloid β production
to study its effects on neurogenic activity of neural stem cells in the adult hippocampus

包装

10, 50 mg in glass bottle

生化/生理作用

NBI 27914 is a CRF1 corticotropin-releasing factor receptor antagonist.

基本信息

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	white
溶解性	DMSO: >20 mg/mL at 60 ℃ H₂O: insoluble
储存温度	2-8℃
SMILES string	CCCN(CC1CC1)c2nc(C)nc(Nc3c(Cl)cc(Cl)cc3Cl)c2Cl
InChI	1S/C18H20Cl4N4/c1-3-6-26(9-11-4-5-11)18-15(22)17(23-10(2)24-18)25-16-13(20)7-12(19)8-14(16)21/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25)
InChI key	KNADXBVKFAUMCR-UHFFFAOYSA-N
Gene Information	human ... CRHR1(1394)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves