Osteopontin from mouse

产品名称：

Osteopontin from mouse
OPN
Early T Lymphocyte Activation Protein-1 (ETA-1)
Secreted Phosphoprotein 1 (Spp1)
Bone Sialoprotein-1

产品介绍：

产品说明

应用

Osteopontin from mouse has been used:

to study its role in a mouse model of preterm brain injury
as a positive control to analyze the relationship between the vascular calcification process and osteopontin (OPN) overexpression in the neointima of atherosclerotic plaques
to study its interaction on the crystal growth process of hydroxyapatite in agarose hydrogels

生化/生理作用

Osteopontin (OPN) is a secreted, highly acidic, calcium binding, phosphorylated glycoprotein that is chemotactic for macrophages, smooth muscle cells, endothelial cells and glial cells. In activated macrophages, OPN inhibits nitric oxide production and cytotoxicity. Human, mouse, rat, pig and bovine OPN share 40% amino acid sequence identity.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.

分析说明

The biological activity is measured by its ability to mediate 293 cell adhesion.

基本信息

MDL编号	MFCD03100698
NACRES	NA.32

产品性质

质量水平	100
生物来源	mouse
重组	expressed in NSO cells
无菌性	sterile
测定	>95% (SDS-PAGE)
形式	lyophilized powder
分子量	30 kDa by SDS-PAGE (reducing) 65 kDa by SDS-PAGE (reducing) (doublet)
包装	pkg of 50 μg
technique(s)	cell culture \| mammalian: suitable
杂质	endotoxin, tested
UniProt登记号	P10923
运输	dry ice
储存温度	−20℃
Gene Information	mouse ... Spp1(20750)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable