产品说明

免疫原

peptide DRFLKIIRPLRNIFLK(C) corresponding to residues 119-134 of human P2Y₁₃ receptor.

目标描述

P2Y₁₃ receptor belongs to the G-protein coupled receptors superfamily. Like the P2Y₁₂ receptor it is a high affinity receptor for the ADP nucleotide, coupled to the Ga_i class of G-proteins. The P2Y₁₃ receptor is highly expressed at brain and spleen tissues as well as in the immune system. ADP activates a negative feedback pathway for ATP release from human red blood cells via the P2Y₁₃ receptor. P2Y₁₃ receptor was also implicated in inhibition of N-type Ca²⁺ channels in neurons, exerting pre and/or post-synaptic modulatory action.

外形

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

重悬

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质