1,2-di-(9Z-octadecenoyl)-<I>sn</I>-glycero-3-[phosphoinositol-3,4-bisphosphate] (ammonium salt); PIP2[3′,4′](18:1(9Z)/18:1(9Z))

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-3,4-bisphosphate] (ammonium salt); PIP2[3′,4′](18:1(9Z)/18:1(9Z))

产品名称：

799268-54-5
18:1 PI(3,4)P2
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-3,4-bisphosphate] (ammonium salt); PIP2[3′,4′](18:1(9Z)/18:1(9Z))
PI (3,4) P2：18:1

产品介绍：

产品说明

一般描述

18:1 PI(3,4)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate)) is an ammonium salt of modified lipid.
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

应用

18:1 PI(3,4)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt)) has been used:

in liposomes/supported lipid bilayer preparation
in liposome co-sedimentation
in the preparation of anionic phospholipid liposomes

生化/生理作用

PI(3,4)P2 can act as a lipid second messenger. In mast cells, PI(3,4)P2 plays a key role in protein kinase B (PKB) phosphorylation on Ser473 sites.

包装

2 mL Amber Serum Vial with Stopper and Crimp Cap (850153P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850153P-100ug)

基本信息

经验(实验)分子式	C₄₅H₉₄N₃O₁₉P₃
分子量	1074.16
NACRES	NA.25

产品性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 100 μg (with stopper and crimp cap (850153P-100ug)) pkg of 1 × 500 μg (with stopper and crimp cap (850153P-500ug))
manufacturer/tradename	Avanti Polar Lipids 850153P
运输	dry ice
储存温度	−20℃
SMILES string	[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+]

安全信息

储存分类代码

13 - Non Combustible Solids