C11 TopFluor^® Ceramide

产品说明

一般描述

Ceramide, a bioactive sphingolipid belongs to the sphingolipid family of cell lipids. This pore-forming member is insoluble in water. It is a hygroscopic and light sensitive lipid.

应用

C11 TopFluor^® Ceramide may be used:

• in the ceramide and B-cell lymphoma-extra-large (Bcl-xL) binding studies to study the effect on ceramide channel formation
• as a tracer in confocal microscopy to treat T84 cells in order to study its localization in sphingomyelinase (SMase)-induced F-actin structures
• to study its effect on the migration of pancreatic cancer stem cells (PCSC) using confocal microscopy

生化/生理作用

Ceramide is known to participate in apoptosis, mediated by mitochondria. Ceramide channels plays a key role in the onset of apoptosis in vivo.

包装

5 mL Amber Glass Screw Cap Vial (810262P-250ug)

法律信息

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

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产品性质

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