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Penciclovir

品牌
Sigma-Aldrich
CAS
39809-25-1
货号
P0035
包装型号
规格纯度
参考价格
1982.65 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
39809-25-1
Penciclovir
BRL-39123
2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one
产品介绍:

产品说明

应用

Penciclovir is a selective antiherpesvirus agent, particularly against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) and varicella-zoster virus (VZV).

包装

100 mg in glass bottle

生化/生理作用

Penciclovir is converted to its active form, penciclovir triphosphate, by cellular kinases. It inhibits viral DNA polymerase by competing with deoxyguanosine triphosphate. It inhibits DNA synthesis of virus-infected cells. Penciclovir has in vitro activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2). It does not inhibit DNA synthesis in non-infected cells. Mode of resistance is via qualitative changes in viral thymidine kinase or DNA polymerase.

其他说明

Keep container tightly closed in a dry and well-ventilated place.

基本信息

经验(实验)分子式C10H15N5O3
分子量253.26
MDL编号MFCD15142866
PubChem化学物质编号329819986

产品性质

质量水平100
溶解性0.02 M potassium phosphate: soluble 2 mg/mL
作用机制DNA synthesis | interferes
enzyme | inhibits
抗生素抗菌谱viruses
SMILES stringNC1=NC(=O)c2ncn(CCC(CO)CO)c2N1
InChI1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18)
InChI keyJNTOCHDNEULJHD-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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