产品说明
应用
(±)-6-Chloro-PB hydrobromide has been used as a dopamine D1 receptor (Drd1a) agonist to study the role of the drd1a-dopamine receptor inactivation of extracellular signal‑regulated protein kinase 1/2 (ERK1/2) in the wild-type and striatum of dopamine-depleted mice. It has also been used as a Drd1a agonist to identify the contribution of D1 (D1R)-like dopamine receptor signaling on learning and memory in Barnes maze in rats.
包装
25, 100 mg in glass bottle
生化/生理作用
(+/-)-6-Chloro-PB HBr is a full D1 dopamine receptor agonist.
注意
Product is air and light sensitive
基本信息
| 经验(实验)分子式 | C16H16ClNO2 · HBr |
| 分子量 | 370.67 |
| MDL编号 | MFCD00153782 |
| PubChem化学物质编号 | 24277934 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 颜色 | white to light tan |
| 溶解性 | H2O: 1.7 mg/mL DMSO: >10 mg/mL ethanol: 6.3 mg/mL |
| SMILES string | Br[H].Oc1cc2C(CNCCc2c(Cl)c1O)c3ccccc3 |
| InChI | 1S/C16H16ClNO2.BrH/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20;/h1-5,8,13,18-20H,6-7,9H2;1H |
| InChI key | RMIJGBMRNYUZRG-UHFFFAOYSA-N |
| Gene Information | human ... DRD1(1812) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
