产品说明
应用
Streptokinase (SK) is commonly used as a thrombolytic agent in the therapy of ischemic stroke. This therapy carries the important risk of intracerebral hemorrhage. Streptokinase is also used in the treatment of complicated parapneumonic effusions and empyema where adverse reactions, allergic type, are rare. The product has been used to measure SK activity in brain heart infusion culture supernatant fluids of the various wild-type and mutant strains of Streptococcus dysgalactiae subsp. Equisimilis.
生化/生理作用
Streptokinase C is an extracellular enzyme that is produced by various strains of β-hemolytic streptococci. It is a single-chain polypeptide that exerts its fibrinolytic action indirectly by activating the circulatory plasminogen.
单位定义
One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 ℃ in 10 min.
外形
Supplied as a frozen solution containing 60 mM phosphate buffer and 0.6 M glutamate. Albumin-free
基本信息
| 酶学委员会(EC)编号 | 3.4.99.0 ( BRENDA | IUBMB ) |
| NACRES | NA.54 |
产品性质
| 质量水平 | 200 |
| 重组 | expressed in E. coli |
| 形式 | buffered aqueous solution |
| specific activity | ≥50,000 units/mg protein |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
