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Anti-XRCC1 antibody produced in rabbit

Anti-XRCC1 兔抗

品牌
Sigma-Aldrich
货号
X0629
规格纯度
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-XRCC1 antibody produced in rabbit
Anti-X-ray repair complementing defective repair in Chinese hamster cells 1
Anti-XRCC1 兔抗
产品介绍:

产品说明

一般描述

X-ray repair cross-complementing group 1 (XRCC1) is a testis enriched protein. It is considered as a DNA repair gene.

免疫原

synthetic peptide corresponding to amino acids 615-633 of human XRCC1, conjugated to KLH via an N-terminal added cysteine residue. The immunizing peptide is identical in mouse and rat.

应用

Anti-XRCC1 antibody produced in rabbit has been used in:

  • immunoblotting
  • immunofluorescence
  • indirect immunofluorescence and telomere FISH (TEL-FISH)
  • protein detection
  • western analysis

生化/生理作用

X-ray repair cross-complementing group 1 (XRCC1) is a molecular scaffold protein that coordinates the assembly of repair complexes at damaged sites. XRCC has been shown to physically interact with several enzymes known to be involved in the repair of SSBs, including DNA ligase IIIa, DNA polymerase b, APE1, polynucleotide kinase (PNK), poly (ADP-ribose), polymerases 1 and 2 (PARP-1 and 2) and others. It participates in the DNA base excision repair (BER) pathway.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01865396

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 85 kDa
species reactivityhuman
浓度~1 mg/mL
technique(s)indirect immunofluorescence: 5-10 μg/mL using MCF7 cells fixed with paraformaldehyde-Triton
western blot: 0.5-1 μg/mL using A431 cell lysates
UniProt登记号P18887
运输dry ice
储存温度−20℃
Gene Informationhuman ... XRCC1(7515)
mouse ... Xrcc1(22594)
rat ... Xrcc1(84495)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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