产品说明
一般描述
Activating transcription factor-2 (ATF-2) belongs to the activator protein 1 superfamily. It is located on human chromosome 2q31.1. It is also known as CREB (cAMP response element binding).
Anti-ATF2 Antibody detects endogenous levels of total ATF2 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human ATF2.
Immunogen Range: 38-87
生化/生理作用
Activating transcription factor-2 (ATF-2) acts as a tumor suppressor gene in breast cancer (BC). It plays a key role in oncogenesis of several mesenchymal tumors. It helps in the multiplication of chondrocytes and growth of cartilage. It also plays an important role in the upregulation of the TH gene (tyrosine hydroxylase) and elongation of catecholaminergic neurons.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01092263 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 52 kDa |
| species reactivity | mouse, human, rat |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI登记号 | P15336 |
| UniProt登记号 | P15336 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ATF2(1386) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
