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Anti-BCL2 (Ab-56) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300339
规格纯度
affinity isolated antibody
参考价格
4610.11 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-BCL2 (Ab-56) antibody produced in rabbit
Anti-B-cell CLL / lymphoma 2 antibody produced in rabbit
Anti-BCL-2 antibody produced in rabbit
产品介绍:

产品说明

一般描述

BCL2 (B-cell lymphoma 2) consists of pro- and antiapoptotic functions. It belongs to BCL2 family of proteins. It is mapped to chromosome 18q21.3 .

免疫原

Peptide sequence around aa. 54-58 (G-H-T-P-H), according to the protein BCL2.

应用

Anti-BCL2 (Ab-56) antibody has been used in western blotting .

生化/生理作用

Overexpression of BCL2 (B-cell lymphoma 2) results in poor clinical predictions in diffuse large B-cell lymphoma (DLBCL). It plays an important role in the growth and progression of cancer.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00239644
NACRESNA.41

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 ~26 kDa
species reactivityhuman
浓度1 mg/mL
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同位素/亚型IgG
免疫原序列(G-H-T-P-H)
NCBI登记号NP_000624.2
UniProt登记号P10415
运输wet ice
储存温度−20℃
Gene Informationhuman ... BCL2(596)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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