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Anti-CSK antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700889
包装型号
规格纯度
参考价格
4668.88 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-CSK antibody produced in rabbit
产品介绍:

产品说明

一般描述

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN, CSK or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.

免疫原

A synthesized peptide derived from human CSK

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivityrat, human, mouse
浓度0.51 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt登记号P41240
运输wet ice
储存温度−20℃
Gene Informationhuman ... CSK(1445)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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