产品说明
一般描述
EPHB1(ephrin type-B receptor 1) and EPHA2 (EPH receptor A2) belongs to the Eph gene family of receptor tyrosine kinases. EPHB1 is present in venous endothelial cells during embryonic development to adulthood. It is located on human chromosome 3q22.2. EPH receptor A2 codes for a 976 amino acid, type-1 transmembrane protein with extracellular NH2-terminal and cytoplasmic COOH-terminal halves.
免疫原
The antiserum was produced against synthesized peptide derived from human EPHB1/2 around the phosphorylation site of Tyr594/604.
Immunogen Range: 561-610
生化/生理作用
EPHB1(ephrin type-B receptor 1) participates in carcinogenesis of RCC (renal cell carcinoma). EPHB1 plays a major role in the growth of nervous and vascular systems. It acts as a biomarker for squamous cell/adenosquamous carcinomas and adenocarcinomas of the gallbladder. EPHA2 (EPH receptor A2) gene is associated with cataracts.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 109 kDa |
| species reactivity | human, rat, mouse |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000 |
| NCBI登记号 | P29317 P54762 |
| UniProt登记号 | P54762 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... EPHA2(1969), EPHB1(2047) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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