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Anti-phospho-JAK2 (pTyr1007) antibody produced in rabbit

抗-磷酸化-JAK2 (pTyr1007) 兔抗

品牌
Sigma-Aldrich
货号
SAB4300124
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-phospho-JAK2 (pTyr1007) antibody produced in rabbit
Anti-Janus kinase 2 (a protein tyrosine kinase) antibody produced in rabbit
Anti-JTK10 antibody produced in rabbit
抗-磷酸化-JAK2 (pTyr1007) 兔抗
产品介绍:

产品说明

一般描述

Janus kinase 2(JAK2) mapped on human chromosome 9p24, encodes a tyrosine kinase. The encoded protein is a member of the Jak family of protein. JAK2 is ubiquitously expressed. This protein contains a catalytic domain and protein–protein interaction domain.

免疫原

Peptide sequence around phosphorylation site of tyrosine 1007 (K-E-Y(p)-Y-K), according to the protein JAK2.

生化/生理作用

Janus kinase 2(JAK2) plays an important role in the activities of cytokines receptors. Overexpression of JAK2 results in neuroblastoma. JAK2 mutations promote primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy. In addition, mutations in the gene has also been observed in polycythaemia vera patients.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Plays a role in leptin signaling and control of body weight.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 ~125 kDa
species reactivitymouse, human, rat
浓度1 mg/mL
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000
同位素/亚型IgG
免疫原序列(K-E-YP-Y-K)
NCBI登记号NP_004963.1
UniProt登记号O60674
运输wet ice
储存温度−20℃
Gene Informationhuman ... JAK2(3717)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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