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Anti-AS160 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200101
规格纯度
~1.5 mg/mL, affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-AS160 antibody produced in rabbit
Anti-Akt substrate of 160 kDa
Anti-TBC1D4 (TBC1 domain family, member 4)
产品介绍:

产品说明

一般描述

AS160 (Akt substrate of 160 kDa, also known as TBC1 domain family member 4 (TBC1D4)) gene is mapped to human chromosome 13q22.2 and encodes a Rab guanosine triphosphatase (GTPase)-activating proteins (RabGAP) protein. AS160 is expressed in many differentiated tissues such as adipocytes and skeletal muscles.

应用

Anti-AS160 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

生化/生理作用

AS160 is known to play an inhibitory role in the transport of glucose transporter 4 (GLUT4) vesicles. It is associated with GLUT4 vesicles in basal states and dissociates in response to insulin. Reduced expression of AS160 in adipocytes has been shown to increase plasma membrane levels of GLUT4 in an insulin-dependent manner.

外形

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~160 kDa
species reactivityhuman
包装antibody small pack of 25 μL
增强验证recombinant expression
Learn more about Antibody Enhanced Validation
浓度~1.5 mg/mL
technique(s)indirect immunofluorescence: 8-16 μg/mL using HEK-293T cells
western blot: 0.8-1.6 μg/mL using extracts of HEK-293T cells over expressing human AS160
UniProt登记号O60343
运输dry ice
储存温度−20℃
Gene Informationhuman ... TBC1D4(9882)
mouse ... Tbc1d4(210789)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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