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Anti-BMI1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200033
规格纯度
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
参考价格
4618.16 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-BMI1 antibody produced in rabbit
Anti-Polycomb group RING finger protein 4
Anti-RNF51
Anti-PCGF4
Anti-B lymphoma Mo-MLV insertion region 1 homolog; ring finger protein 51
产品介绍:

产品说明

一般描述

The human proto-oncogene BMI1 (also known as Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, and RING finger protein 51) is a member of the mammalian Polycomb group (Pc-G) genes.

应用

Anti-BMI1 antibody produced in rabbit may be used in several immunochemical techniques including immunoblotting (~37 kDa) and immunofluorescence.

生化/生理作用

BMI1 (Proto-Oncogene, Polycomb Ring Finger) plays an important role as epigenetic gene silencers during development. Elevated expression of BMI1 is associated with many cancers such as mantle cell lymphoma, B-cell non-Hodgkin′s lymphoma, myeloid leukemia, non-small cell lung cancer, colorectal cancer, breast cancer and prostate cancer. BMI1 has been shown to be also required for self-renewal of hematopoietic stem cells and neuronal stem cells. BMI1 knockout in mice results in defects in hematopoiesis, skeletal patterning and neurological functions.

外形

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~37 kDa
species reactivityhuman
包装antibody small pack of 25 μL
浓度~1.0 mg/mL
technique(s)indirect immunofluorescence: 1-2 μg/mL using paraformaldehyde fixed HEK-293T cells over expressing human BMI1
western blot: 1-2 μg/mL using lysate of HEK-293T cells over expressing human BMI1
UniProt登记号P35226
运输dry ice
储存温度−20℃
Gene Informationhuman ... BMI1(648)
mouse ... Bmi1(12151)
rat ... Bmi1(307151)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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