产品说明
一般描述
BMPR-1A (bone morphogenic protein receptor type 1A) signaling is known to be important for inner root sheath differentiation, hair follicle cycling and tooth development. Mutations in BMPR-1A are a common cause of juvenile polyposis syndrome (JPS). BMPR-1A is expressed in a high quantity during the formation of the primary and secondary palate and the loss of BMPR-1A could be a cause for the cleft palate birth defect.
特异性
This antibody recognizes BMPR-1A at the extracellular domain.
免疫原
KLH-conjugated linear peptide corresponding to the extracellular domain of human BMPR-1A.
Epitope: Extracellular domain
应用
Research Category
Stem Cell Research
Research Sub Category
Kinases & Phosphatases
Anti-BMPR-1A Antibody is an antibody against BMPR-1A for use in WB.
质量
Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected BMPR-1A on 10 µg of NIH/3T3 cell lysate.
目标描述
~75 kDa observed. The calculated molecular weight is 67 kDa; however, BMPR-1A has been shown as a ~77 kDa band in western blots (Koenig, B., et al. (1994). Molecular and Cellular Biology. 14(9):5961-5974).
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
NIH/3T3 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, mouse, rat |
technique(s) | western blot: suitable |
NCBI登记号 | NP_004320 |
UniProt登记号 | P36894 |
运输 | wet ice |
Gene Information | human ... BMPR1A(657) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich