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Anti-KU80 antibody, Rabbit monoclonal

品牌
Sigma-Aldrich
货号
SAB5500135
规格纯度
recombinant, expressed in proprietary host, clone SP130, affinity isolated antibody
参考价格
4661.96 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-KU80 antibody, Rabbit monoclonal
产品介绍:

产品说明

一般描述

X-ray repair cross-complementing protein 5 (XRCC5), alternative name (Ku80), is single stranded DNA-dependent ATP-dependent helicase. It involves in chromosome translocation. Ku80 along with Ku70 forms a heterodimeric protein originally identified as autoantigens associated with several autoimmune diseases including scleroderma, polymyositis and systemic lupus erythematosus. Ku is widely expressed nuclear protein that binds to and stabilizes the ends of DNA at telomeres or double-stranded DNA breaks. The inhibition of Ku80 can damage the DNA repair pathway of tumor cells and potentially increase the killing of cancer cells, and reduce drug resistance.

免疫原

Synthetic peptide corresponding to an internal region within Human Ku80 aa 700 to the C-terminus.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
重组expressed in proprietary host
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆SP130, monoclonal
species reactivityhuman (tested)
species reactivity (predicted by homology)rat, bovine, mouse
technique(s)immunoblotting: 1:25
immunohistochemistry: 1:100
同位素/亚型IgG
UniProt登记号P13010
运输wet ice
储存温度2-8℃
Gene Informationhuman ... XRCC5(7520)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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