产品说明
一般描述
Phosphacan is a soluble nervous tissue-specific proteoglycan that is thought to regulate axonal outgrowth. It is synthesized by glia and binds to neurons and to the neural cell adhesion molecules tenascin, N-CAM or NG-CAM but not to laminin and fibronectin. Phosphacan acts as a potent inhibitor of cell adhesion and neurite outgrowth.
特异性
Phosphacan (Receptor Tyrosine Phosphatase Beta). Recognizes the core protein.
应用
Western blot. Recognizes bands at 250, 190, and 180 kDa on western blots of embryonic rat brain extracts.
Immunocytochemistry: 1:10
Immunohistochemistry on 4% paraformaldehyde fixed tissue: 1:1,000
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Anti-Phosphacan Antibody, clone 122.2 detects level of Phosphacan & has been published & validated for use in WB, IC, IH.
Research Sub Category
Growth Cones & Axon Guidance
外形
Ascites fluid. Liquid. Contains no preservative.
储存及稳定性
Maintain at -20°C in undiluted aliquots up to 6 months. Avoid repeated freeze/thaw cycles.
分析说明
Control
POSITIVE CONTROL:
embryonic or early post-natal rat brain.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | ascites fluid |
antibody product type | primary antibodies |
克隆 | 122.2, monoclonal |
species reactivity | rat |
manufacturer/tradename | Chemicon® |
technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgM |
UniProt登记号 | Q62656 |
运输 | dry ice |
Gene Information | human ... PTPRZ1(5803) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich