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Anti-Phospho-AKT1-S124 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701826
包装型号
规格纯度
参考价格
4266.29 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Phospho-AKT1-S124 antibody produced in rabbit
产品介绍:

产品说明

一般描述

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]

免疫原

A phospho specific peptide corresponding to residues surrounding S124 of human AKT1

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivityhuman
浓度1.43 mg/mL
technique(s)western blot: 1:500-1:1000
UniProt登记号P31749
运输wet ice
储存温度−20℃
Gene Informationhuman ... AKT1(207)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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