产品说明
一般描述
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer′s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
免疫原
A phospho specific peptide corresponding to residues surrounding Y133 of human alpha-Synuclein.
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | liquid |
species reactivity | mouse, human |
浓度 | 1.51 mg/mL |
technique(s) | western blot: 1:500-1:2000 |
UniProt登记号 | P37840 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... SNCA(6622) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich