产品说明
一般描述
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell′s DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
免疫原
A synthetic phosphorylated peptide around T71 of human ATF2 (NP_001871.2).
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at -20℃. Avoid freeze / thaw cycles.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 13- 15 23-24 35-54 |
| species reactivity | mouse, rat, human |
| 浓度 | 3.24 mg/ml |
| technique(s) | immunofluorescence: 1:50-1:100 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| UniProt登记号 | P15336 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ATF2(1386) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
