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位置:首页 > 品牌 > Sigma-Aldrich > Anti-phospho-PKD1/2/3/PKC mu (pSer738+Ser742) antibody produced in rabbit

Anti-phospho-PKD1/2/3/PKC mu (pSer738+Ser742) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4504061
规格纯度
affinity isolated antibody
参考价格
4618.16 *本价格含增值税费
促销
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数量
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产品名称:
Anti-phospho-PKD1/2/3/PKC mu (pSer738+Ser742) antibody produced in rabbit
产品介绍:

产品说明

一般描述

Protein kinase D1 (PRKD1) belongs to the protein kinase D family. It is a serine/threonine kinase which is expressed in mammary glands. The gene encoding this protein is localized on human chromosome 14q12.

免疫原

The antiserum was produced against synthesized peptide derived from human PKD1/2/3/PKC mu around the phosphorylation site of Ser738 and Ser742.

Immunogen Range: 706-755

生化/生理作用

Protein kinase D1 (PRKD1) has a role in insulin secretion in the islets of Langerhans. The protein is involved in various cellular processes like DNA synthesis, cell cycle progression, initiation of the nuclear factor κB pathway, vesicular trafficking and apoptosis. It conserves epithelial phenotype by inhibiting epithelial-to-mesenchymal transition. PRKD1 acts as an effector of diacylglycerol and protein kinase C. Protein kinase D2 (PRKD2) is a mediator of tumor cell-endothelial cell communication. PRKD2 influences CD8+ T cell-dependent immune responses. It facilitates cell migration and it is associated with the progression and maintenance of various malignancies.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 101 kDa
species reactivityhuman, mouse, rat
浓度~1 mg/mL
technique(s)ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号O94806
Q15139
Q9BZL6
UniProt登记号Q9BZL6
运输wet ice
储存温度−20℃
Gene Informationhuman ... PRKD1(5587), PRKD2(25865), PRKD3(23683)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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