产品说明
一般描述
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
免疫原
A phospho specific peptide corresponding to residues surrounding S780 of human RB
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | human |
| 浓度 | 0.49 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:100 immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
| UniProt登记号 | P06400 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... RB1(5925) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
