产品说明
一般描述
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
免疫原
A phospho specific peptide corresponding to residues surrounding T446 of human PKR/EIF2AK2
外形
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | monoclonal |
| 形式 | liquid |
| species reactivity | rat, human, mouse |
| 浓度 | 0.84 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt登记号 | P19525 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... EIF2AK2(5610) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
