产品说明
一般描述
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
免疫原
A phospho specific peptide corresponding to residues surrounding S727 of human STAT1
外形
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | monoclonal |
| 形式 | liquid |
| species reactivity | human |
| 浓度 | 0.64 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt登记号 | P42224 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... STAT1(6772) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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