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Anti-PRKAB1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700079
包装型号
规格纯度
参考价格
4314.62 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-PRKAB1 antibody produced in rabbit
PRKAB1
AMPK
HAMPKb
产品介绍:

产品说明

一般描述

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human PRKAB1 (NP_006244.2).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 30
species reactivityrat, mouse, human
浓度1.94 mg/ml
technique(s)immunofluorescence: 1:50-1:100
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:2000
UniProt登记号Q9Y478
运输wet ice
储存温度−20℃
Gene Informationhuman ... PRKAB1(5564)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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