产品说明
一般描述
Septins are cytoskeletal GTPases. SEPT8 (septin 8) belongs to septin family. It is expressed in brain. It is also present in heart, aorta, prostate, testis and ovary. It is located on human chromosome 5q31.
Anti-SEPT8 Antibody detects endogenous levels of total SEPT8 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human SEPT8.
Immunogen Range: 170-219
生化/生理作用
In platelets, SEPT8 (septin 8) participates in granula secretion. It also participates in cytokinesis, vesicle trafficking and exocytosis. The protein mitogen-activated protein kinase-activated protein kinase 5 (MK5) phosphorylates and modulates septin 8, which interacts with various synaptic vesicle proteins and may participate in the release of neurotransmitters.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 55 kDa |
| species reactivity | human, rat, mouse |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 western blot: 1:500-1:1000 |
| NCBI登记号 | Q92599 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SEPT8(23176) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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