产品说明
一般描述
TRIM59 (tripartite-59) belongs to the tripartite motif (TRIM) family of proteins. It has a RING domain, one or two B-box motifs and a coiled-coil region. It is located on human chromosome 3q25.
Anti-TRIM59 Antibody detects endogenous levels of total TRIM59 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human TRIM59.
Immunogen Range: 191-240
生化/生理作用
Suppression of tripartite-59 (TRIM59) blocks the multiplication and migration of cervical cancer cells. In prostate cancer models, TRIM59 serves as a proto-oncogene that affects Ras and RB signal pathways. It also induces the multiplication and migration of non-small cell lung cancer cells.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 47 kDa |
| species reactivity | mouse, human |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI登记号 | Q8IWR1 |
| UniProt登记号 | Q8IWR1 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TRIM59(286827) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
