产品说明
特点和优势
The azido-dPEG®8 contains an azide function on one end of a single molecular weight dPEG® spacer (32.2Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
基本信息
| 经验(实验)分子式 | C19H37N3O10 |
| 分子量 | 467.51 |
| MDL编号 | MFCD21363300 |
| PubChem化学物质编号 | 329823934 |
| NACRES | NA.22 |
产品性质
| 测定 | >90% |
| 形式 | solid or viscous liquid |
| reaction suitability | reaction type: click chemistry reagent type: cross-linking reagent reaction type: click chemistry |
| 聚合物结构设计 | shape: linear functionality: heterobifunctional |
| 运输 | ambient |
| 储存温度 | −20℃ |
| SMILES string | OC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
