产品说明
一般描述
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor α/β and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at N-terminus, was expressed in E.coli.
外形
1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
产品性质
生物来源 | human |
重组 | expressed in E. coli |
测定 | ≥90% (SDS-PAGE) |
形式 | liquid |
分子量 | 13.1 kDa (117 aa, 23-116 aa + His tag) |
包装 | pkg of 100 μg |
浓度 | 1 mg/mL |
杂质 | <1 EU/μg endotoxin (LAL test) |
UniProt登记号 | P09693 |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... CD3G(917) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich