产品说明
一般描述
CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form.
生化/生理作用
CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients.
外形
Lyophilized from PBS
重悬
Reconstitute with 100 μL deionized water.
其他说明
Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
法律信息
FLAG is a registered trademark of sigma-aldrich Co. LLC
产品性质
| 生物来源 | human |
| 重组 | expressed in CHO cells |
| 标签 | FLAG® tagged |
| 测定 | >95% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | 35-40 kDa by SDS-PAGE |
| 包装 | pkg of 10 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | <0.01 EU/μg endotoxin, tested |
| UniProt登记号 | P29965 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CD40LG(959) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
