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CD58/LFA-3 human

品牌
Sigma-Aldrich
货号
SRP6432
规格纯度
recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
参考价格
3896.85 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
CD58/LFA-3 human
AG3
产品介绍:

产品说明

一般描述

Cluster of differentiation 58 (CD58), also known as lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on antigen presenting cells (APC), particularly macrophages. The gene encoding this protein is localized on human chromosome 1p13.1.
CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

生化/生理作用

Cluster of differentiation 58 (CD58)/lymphocyte function-associated antigen 3 (LFA-3) is a ligand of the T-lymphocyte cluster of differentiation 2 (CD2) glycoprotein, which binds to CD2 (LFA-2) on T cells. It is important in strengthening the adhesion between the T cells and professional antigen presenting cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in HEK 293 cells
标签6-His tagged (C-terminus)
测定≥95% (SDS-PAGE)
形式lyophilized
分子量calculated mol wt 22.3 kDa
observed mol wt 30-45 kDa (DTT-reduced. Protein migrates due to glycosylation. Phe 29 is the predicted N-terminal.)
包装pkg of 10 μg
pkg of 50 μg
UniProt登记号P19256 
运输wet ice
储存温度−20℃
Gene Informationhuman ... CD58(965)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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