产品说明
一般描述
Platelet factor-4 (PF-4) or chemokine (C-X-C motif) ligand 4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. Recombinant human CXCL4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
生化/生理作用
Platelet factor-4 (PF-4) or chemokine (C-X-C motif) ligand 4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. This protein associates with heparin and neutralizes it. It also neutralizes various negatively charged proteoglycans.
外形
0.25 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 2 mM DTT and 50% glycerol.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥85% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | 10 kDa (91 aa, 32-101 aa + His Tag) |
| 包装 | pkg of 20 μg |
| 浓度 | 0.25 mg/mL |
| UniProt登记号 | P02776 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... CXCL4(5196) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H319 |
| 预防措施声明 | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| 危险分类 | Eye Irrit. 2 |
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
