Hexaminolevulinate hydrochloride

产品名称：

140898-91-5
Hexaminolevulinate hydrochloride
5-Aminolevulinic acid hexyl ester hydrochloride
5-Aminolevulinic acid hexyl ester HAL hydrochloride
Hexyl 5-aminolevulinate hydrochloride
Hexvix
HAL
P 1206
n-Hexyl 5-aminolevulinate hydrochloride

产品介绍：

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis.

基本信息

经验(实验)分子式	C₁₁H₂₁NO₃ · HCl
分子量	251.75
MDL编号	MFCD03695491
PubChem化学物质编号	329825978

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 20 mg/mL, clear
储存温度	room temp
SMILES string	CCCCCCOC(CCC(CN)=O)=O.[H]Cl
InChI	1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H
InChI key	LZYXPFZBAZTOCH-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3