产品说明
应用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
生化/生理作用
Fibroblast growth factor 21 (FGF-21) plays a vital role in the regulation of glucose uptake in mouse 3T3-L1 and primary human adipocytes. In addition, it is also implicated in lipid metabolism and in energy balance. FGF-21 plays a key role in controlling oxidative stress cell response. Overexpression of the gene has been associated with the development of acute pancreatitis, obesity, insulin resistance and metabolic syndrome. Additionally, elevated expression of FGF-21 has been observed in patients with insulin resistance and type 2 diabetes mellitus (T2DM). Thus, it can be considered as a potent target for an effective treatment of diabetes.
其他说明
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
基本信息
| NACRES | NA.32 |
产品性质
| species reactivity | human |
| 包装 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable |
| input | sample type plasma sample type serum sample(s) sample type cell culture supernatant(s) |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 8 pg/ml |
| detection method | colorimetric |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FGF21(26291) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H290 |
| 预防措施声明 | P234 - P390 |
| 危险分类 | Met. Corr. 1 |
| 储存分类代码 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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